Publish Date
Date
March 06, 2025
Blog Category
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Blogs

Aspirin helps the immune system to recognize and kill metastasizing cancer cells

Aspirin has been called a wonder drug. And it’s easy to see why.
A surprising discovery found that the common painkiller aspirin found in your medicine cabinet may even have the power to stop cancer from spreading, thus preventing many deaths.
According to researchers from the University of Cambridge, aspirin can lower the risk of certain types of cancer, including those involving the colon, ovaries, liver, and even prostate. For scientists, this is so strong that many health guidelines recommend daily aspirin use for certain groups of people, including adults ages 50 to 59 with heart issues and those with an inherited tendency to develop colon polyps and cancer.

How does aspirin reduce cancer spread?

Scientists say the drug helps the immune system recognize and kill metastasizing cancer cells, thereby preventing the spread.
This breakthrough finding could change the way cancer is treated in the future.
The study, published in Nature Journal, focuses on the body’s immune system and a previously hidden role that aspirin plays in unleashing T-cells—the body’s cancer-fighting soldiers—to attack rogue cancer cells before they spread. It disrupts the platelets, freeing up the T cells, allowing them to unleash their full cancer-killing power, and giving the immune system a much-needed edge in the fight against cancer. While still in the early stage, the findings show that there is a possibility of how an everyday drug can work wonders in fighting the deadly cancer.
The university has also released data that shows that those who took daily aspirin are more likely to survive if they were ever diagnosed with cancer.
"What we have discovered is that aspirin might work, surprisingly, by unleashing the power of the immune system to recognize and kill metastasizing cancer cells," Prof. Rahul Roychoudhuri from the University of Cambridge told BBC. According to Prof. Roychoudhuri, the drug could work best in cancers that are caught at early stages and could be used after treatment, such as surgery, to help the immune system detect any cancer that may have already spread.

Side effects of aspirin

Even though the study provides important clues on aspirin’s positive influence on preventing cancer spread, experts believe it comes with its own set of risks, which include:
  • Aspirin causes dangerous internal bleeding including strokes
  • It is also not clear whether the effect works for all cancers or just specific ones
Those who have Lynch syndrome - a genetic condition that raises cancer risk, are already advised to take aspirin. However, experts stress that more clinical trials are needed to determine if other cancer patients could benefit.
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