Publish Date
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February 22, 2025
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Fibrosis happens due to the development of scar tissue especially in those who are obese

Hypertension or high blood pressure, is known as a silent killer because, without any visible signs and symptoms, it leads to years of damage to organs. According to experts, the influence of high blood pressure on your liver has traditionally been underestimated, despite various studies indicating that it might be involved in liver fibrosis.
Fibrosis in your liver happens due to the development of scar tissue, especially in those who are obese or have metabolic syndrome. According to doctors, it can get far worse if not treated in time. “It can lead to cirrhosis if left untreated and undiagnosed. Conditions such as hepatitis or alcohol abuse are usually associated with liver injury, but hypertension has been proven to play a vital role as well,” Dr. Bhavesh Patel, Consultant Gastroenterologist, Bhailal Amin General Hospital, told Times Now.

What happens in fibrosis of the liver?

According to Dr. Patel, continuous and unchecked hypertension impacts the liver by raising vascular pressure, which interferes with blood flow. “Hypertension may lead to microvascular injury, which results in tiny tears or injuries in blood vessels, and this provokes an inflammatory reaction. This reaction initiates stellate cells, which are major contributors to fibrosis development,” he said.
"When activated, these cells synthesize collagen and other materials that substitute normal liver tissue with scar tissue,” Dr. Patel added.
A few other reasons for liver fibrosis include:
  • Insulin resistance
  • Obesity
  • High cholesterol
All of these factors lead to the development of non-alcoholic fatty liver disease, which evolves into non-alcoholic steatohepatitis and eventually results in liver fibrosis.

Signs and symptoms of fibrosis

In its initial phase, fibrosis is usually asymptomatic, but there are some subtle symptoms to look out for which include:
  • Weakness
  • Jaundice
  • Dark-coloured urine
  • Light-coloured poop
  • Digestive difficulties, especially with fats.
  • Weight loss and muscle loss.
  • Mild brain impairment
  • Abdominal pain
  • A sense of fullness in the upper right quadrant of the abdomen
  • Easy bruising

How to prevent fibrosis?

According to Dr. Patil, a few ways to avoid liver fibrosis in people with high blood pressure are:

Maintain a healthy diet

Emphasise whole foods, with plenty of plants and lean protein.

Maintain a healthy BMI

Make sure to keep your weight under the prescribed limits and get over obesity by following a healthy diet and regular workouts.

Avoid alcohol

It is important to quit tobacco and nonprescription drug use along with drinking alcohol, which is like a poison for your liver health.

Take medications only as directed

Always make sure to discuss new medications with your doctor.

Protect yourself from infections

Practice good hygiene and safe sex to avoid additional burdens on your liver.

Keep up with your healthcare appointments

Get your regular screenings to catch complications early.
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